MetaSystems Probes has received IVDR certification for our initial 26 fluorescence in situ hybridization (FISH) probes from the notified body, BSI. Achieving this milestone was not without its challenges, and we are delighted to have accomplished IVDR certification for this probe set at an early stage.

MetaSystems Probes participated in the 35th Tumor Genetics Workshop 2023 (Tumorgenetische Arbeitstagung) in Rostock, Germany.

MetaSystems India participated in a two-day hands-on FISH workshop on April 4-5.

Last week, MetaSystems India participated in a one-day hands-on FISH workshop.

Today, MetaSystems Probes introduces 4 new probes in the field of hematology and postnatal diagnostics: XL t(11;14) CCND1/IGH DF, XL CCND3/IGH DF, XL CUX1/EZH2/7cen, and XL DiGeorge TBX1.

Today, MetaSystems Probes introduces 4 new probes in the field of hematology and oncology. XL t(5;11) NSD1/NUP98 DF, XL ETV6 BA, XL PAX5 BA, and XL 5p15/21q22 are intended as diagnostic tools for detecting recurrent aberrations described in acute myeloid leukemia (AML), acute lymphoblastic leukemia (ALL), and multiple myeloma (MM).

After a year full of challenges and changes, there is no better time to thank our customers, partners, and friends for their loyalty and trust. We appreciate your understanding for any delays due to the exceptional situation and look forward to supporting you with our products and services in 2023.

It was a great pleasure to meet our distributors from around the world for the 20th time.

Today, MetaSystems Probes introduces 3 new break apart probes detecting critical rearrangements in acute lymphoblastic leukemia (ALL) and T-cell prolymphocytic leukemia (T-PLL) involving the gene loci of SPI1, CSF1R and TCL1.

Theresia Bauer, Minister of Science, Research and the Arts for the State of Baden-Württemberg, Germany visited MetaSystems to get an impression of the work of this 'Hidden Champion' in life sciences sector.

MetaSystems Probes is pleased to announce the new catalog 2021/2022 including our new RNA FISH probes for COVID-19 research. A PDF version of the new catalog is available for download in the download section of our website.

Researchers led by dermatologist Raffaele Gianotti of the University of Milan and pathologist Prof. Massimo Barberis, director of the Molecular Pathology Unit at Institute of European Oncology in Milan, report evidence of early SARS-CoV-2 infection in an Italian patient.

An unusual year is now almost behind us. We would like to thank all our customers, partners and friends for staying with us through these difficult times.

MetaSystems Probes is proud to present our new XRNA product line! It consists of five different RNA FISH probes intended for multifaceted applications. Our XRNA SARS-CoV-2 probe can be used to detect viral RNA in cell and tissue samples, while automation and quantification can be provided by MetaSystems’ slide scanning platform Metafer. The remaining probes are designed for expression analysis of two central proteins of SARS-CoV-2 viral host-cell-entry (ACE2 and TMPRSS2), and the housekeeping gene (PGK1). Additionally, we offer an XRNA probe for RNA expression analysis of the immune checkpoint component PD-L1.

Our XRNA probes can be used for analysis of many different sample types including cellular samples from swabs, sputum, bronchoalveolar lavage and tissue sections.

MetaSystems Probes is further expanding its microdeletion portfolio and adds two new probes for the detection of Prader-Willi/Angelman and Smith-Magenis/Miller-Dieker.

Today, MetaSystems Probes, MetaSystems Hard & Software and PixelBiotech are proud to announce a new high-performance solution for RNA-based detection of SARS-CoV-2 in cell and tissue samples. Find out more...

Today, MetaSystems Probes introduces 5 new dual fusion probes detecting frequent acute myeloid leukemia (AML)/acute lymphoblastic leukemia (ALL) associated KMT2A rearrangements.

The outbreak of the SARS-CoV-2 virus has led to global efforts to understand the mechanisms of the virus-induced Covid-19 disease and to seek to find effective countermeasures. In this context, our daughter company MetaSystems Italy joined forces with RNA-FISH specialist PixelBiotech for development of highly sensitive and precise SARS-Covid-2 probes.

Download the leaflet with details about the new technology here.

Today, MetaSystems Probes provides the acute myeloid leukemia (AML) FISH Guide leaflet. Based on two widely accepted risk stratification models and the ‘WHO Classification of Tumours of the Haematopoietic and Lymphoid Tissues’, this informative brochure summarizes AML associated entities, their underlying chromosomal aberrations and the appropriate MetaSystems FISH probes for detection.

Against the background of the worldwide appearance of the Corona virus (Sars CoV-2), the most important task for everyone at present is to contribute to slowing down its speed of propagation by adapting their behavior. Nevertheless, we are striving to maintain our services as far as possible and provide our customers and partners with the usual good service.

Today, MetaSystems Probes introduces a new tool to comfortably download the Certificates of Analysis (CoA) from our CoA Database.

Today, MetaSystems Probes expands its product portfolio introducing four new probes in the field of pathology and hematology.

About 100 guests from 36 countries met on the XVIII. MetaSystems Distributor Meeting (DM) in November to exchange experiences and to get to know new trends and developments at MetaSystems.

MetaSystems Probes launches two new probes for the detection of CRLF2-rearrangements in the context of BCR-ABL1-like ALL.

MetaSystems is further expanding its portfolio and adds three probes for the detection of frequent microdeletion syndromes.

Neon, the outstanding MetaSystems case and image management system, offers many tools and helpful gadgets to streamline routine workflows, for example in cytogenetics labs. The second MetaSystems User Day, addressed to MetaSystems clients from Germany, Austria, and Switzerland, provided in different workshops knowledge helping to unleash the full power of the system.

The Congress 'Genetics of XXI Century' in Moscow, Russia (May 2019) has been one of the most important events for the professional international community of geneticists. Our partner company in Russia OOO MetaSystems considered it a good occasion to present the new camera CoolCube 4 connected to a state-of-the-art Neon system to the public.

N.N.Burdenko National Scientific and Practical Center for Neurosurgery is one of the first MetaSystems’ customers in Russia who implemented FISH on tissues into their daily practice ( in the late 90ies). Our partner in Russia, OOO MetaSystems therefore provides comprehensive support of all initiatives shown by the head of pathology lab and its staff.

The new, 172-page product catalog from MetaSystems Probes is now also available in Chinese language. A PDF file of the new catalog is available for download here on the download section of the MetaSystems Probes website.

We are very pleased to announce two new innovations in our XCyting Locus-Specific Probes product line for Hematology and Oncology.

The meeting of the German Society of Human Genetics (gfh) was held in Weimar, Germany this week and of course the attendees had the opportunity to visit the joined booth of MetaSystems and MetaSystems Probes. Main topics of the exhibition have been the latest advancements of the Neon case and imaging platform and RapidHyb, the revolutionary fast hybridization times of MetaSystems Probes' FISH probes.

An "International Workshop on Genomic Instability: Basic and Applied Aspects" was jointly organized by Environmental Mutagen Society of India (EMSI) and School of Bio-sciences and Technology, Vellore Institute of Technology under the guidance of Prof. Wilner Martinez-Lopez (Biological Research Institute “Cemente Estable”-Uruguay, IIBCE) and Prof. Radha Saraswathy (School of Bio-sciences and Technology, VIT).

Fluorescence in situ hybridization has become an essential detection assay in today´s routine diagnostics. However, long hybridization times of many hours to overnight are still a restrictive factor. We have refined the production process of our FISH probes to reduce background and artefacts and to improve the signal to noise ratio, particularly in short-time hybridization. Since mid-2015, one hour hybridization on lymphocytes is an integral part of quality control for all XCyting locus-specific probes at our manufacturing facility.

Fluorescence in situ hybridization has become an essential detection assay in today´s routine diagnostics. However, long hybridization times of many hours to overnight are still a restrictive factor. We have refined the production process of our FISH probes to reduce background and artefacts and to improve the signal to noise ratio, particularly in short-time hybridization. Since mid-2015, one hour hybridization on lymphocytes is an integral part of quality control for all XCyting locus-specific probes at our manufacturing facility.

MetaSystems proudly announces the opening of our first subsidiary in the Southern hemisphere. The new office is located in Buenos Aires, Argentina and bears the name MetaSystems Latinoamérica SAS (MetaSystems LatAm). The foundation has been the response to the growing demand on technical knowledge and 'know how' experienced in the last years all over the Latin American territories. MetaSystems LatAm takes care for the organization of sales, support, and customer relation activities in all countries in Latin America. It will manage distributor companies and contacts in the region, and it will facilitate communication between end-users, distributors and headquarters in Germany.

A “Hands-on Workshop on FISH and its application in Pathology and Clinical Medicine” was organized by MetaSystems and Department of Pathology, Himalayan Institute of Medical Sciences (HIMS) to demonstrate the applications of FISH in hematological malignancies and solid tumors.

The yearly MetaSystems Distributor Meeting (DM), brought into life in 2002 as a platform to gather all international partners of MetaSystems and other members of the global MetaSystems family, just ended last week. The DM is being organized in turns by MetaSystems Headquarters, MetaSystems USA (MGI), and MetaSystems Asia. Since MGI is celebrating its 25th anniversary in 2018 they decided to choose a special location: Nassau, The Bahamas!

As the first abroad office of MetaSystems, MetaSystems Group, Inc. (MGI) will turn 25 years in 2019. Therefore the company, being the official organizer of the 2018 MetaSystems Distributor Meeting (DM) took advantage of this fact and Dr. Uli Klingbeil, founder of MGI, presented the history of the company on this event. As an acknowledgement of all staff members who helped turning MGI into the thriving enterprise it today is, the company celebrated its birthday on the white sands of the Bahamas, next to Nassau on New Providence Island.

MetaSystems is further expanding its portfolio and adds several new probes for hematology.

Sarcomas are representing a heterogeneous group of tumors originating from mesenchymal tissue. Around 80% develop from soft tissue, the remaining 20% from bone. Sarcomas are frequently observed in children and young adults, accounting for more than 20% of all pediatric neoplasms. Due to the diversity, more than 100 subtypes are known to date, the diagnosis of sarcomas is challenging and fluorescence in situ hybridization has become a valuable tool to analyze the molecular signature of sarcoma subtypes today.

The first MetaSystems User Day took place in Altlussheim, Germany in the last week of September 2018. Approximately 25 guests took the opportunity to learn about the benefits of Neon, RapidScore, and the latest MetaSystems FISH probes.

MetaSystems attended the 2018 International Congress of Genetics being held in Foz do Iguacu, Brazil. The conference is known as one of the most important gatherings in the field of genetics in Latin America. Accordingly, the MetaSystems booth traffic was very busy. People from many Latin American countries took the opportunity to learn more about the latest MetaSystems products including Neon, Metafer, and the latest probes.

We are pleased to inform you about the collaboration we recently have concluded with our new partner in France. AmpliTech is appointed as the exclusive distributor of MetaSystems Probes. AmpliTech is distributing our FISH probes products and provides technical support to existing and new customers.

MetaSystems is further expanding it´s portfolio in the field of pathology and hematopathology.

XCyting Locus-Specific Probes for Aneuploidy Detection

MetaSystems is launching the XA AneuScore III Probe Kit combining the advantages of the well-known products XA AneuScore I and XA AneuScore II. XA AneuScore III comprises XA 13/18/21 and XA X/Y/18. The locus specific probes of XA 13/18/21 ensure clear and condensed signals with low background in interphase FISH assays. XA X/Y/18 centromeric signals allow the detection of sex chromosome aneuploidies supported by additional signals in the centromere region of chromosome 18.

MetaSystems is launching the XA AneuScore III Probe Kit combining the advantages of the well-known products XA AneuScore I and XA AneuScore II.

 A joint FISH workshop was organized by Cytogenetics Department, Tata Medical Center (Dr Mayur Parihar and Team) along with MetaSystems on 4th and 5th May to demonstrate FISH in hematological malignancies and solid tumors.

The 3rd International and 15th Iranian Genetic Congress in Tehran was held last week. Our partner VITCO / Vira Idea Trade Co. represented MetaSystems and MetaSystems Probes on the industrial exhibition.

MetaSystems and MetaSystems Probes performed a workshop with exercises in classical FISH hybridization, short time hybridization, RapidScore analysis with Metafer and imaging with Isis. The workshop was done in two groups from Feb. 02 to Feb. 05 in Dubai. UAE.

MetaSystems is introducing two new probes, XL 2p11 IGK BA and XL 22q11 IGL BA, replacing XL IGK and XL IGL, respectively.

MetaSystems is very proud to announce the XL CBFB/MYH11 plus translocation/dual fusion probe today. Always listening to our customers, we have revitalized this product as a complement to our well proven XL CBFB break apart probe.

Since 16 years, the MetaSystems Distributor Meeting (DM) is the annual get-together for all members of the global MetaSystems family. Staff of all MetaSystems offices, of partner companies, and of local sales organizations met in November 2017 to discuss the latest MetaSystems developments and achievements. The 2017 DM was held in the light of two major events, namely, (a) the launch of the first release version of Neon, the image and case database for all MetaSystems products and (b) the latest diversification on the field of microbiology applications.

MetaSystems held its second workshop in the Middle East this year between the 18th and 21st of February in Dubai, UAE. This time, in addition to a system demonstration, a probes workshop was also included. Over the course of two different workshops (one on the 18th/19th, one on the 20th/21st), 29 participants from 5 countries experienced the ease and quality of MetaSystems FISH probes, software, and hardware. Participants came from Pakistan, Iran, the UAE, Oman, and Lebanon.

For the first time this year, MedLab in Dubai, the world’s largest laboratory exhibition and congress, took place separately from the ArabHealth. Being a leader in microscope based imaging, MetaSystems decided to attend this event in 2017 and to take advantage of direct contacts to regional sales representatives, partner companies, and customers. All companies of the MetaSystems family, namely MetaSystems, MetaSystems Probes, and for the first time MetaSystems Indigo were present at the booth and provided latest news on their respective products and innovations.

Our US team was recently awarded ISO 13485 certification! Here are some pictures taken during the celebration. At MetaSystems, we strive after continuously improving the quality of our service and products!

The XV. MetaSystems Distributor Meeting (DM) has taken place in Hong Kong in from December 06. - 08. Since 2002, MetaSystems and MetaSystems Probes invite distributors and partners from all countries to learn about latest product and application developments, to exchange their market experience with others, and to deepen the friendship of all members of the MetaSystems family.

MetaSystems is very proud to announce that it has now been active and independent for 3 full decades. Back in the late nineteen-eighties, MetaSystems' began its humble but promising journey. From the seed of just one brilliant idea grew an incomparable company. Thirty years later, the company is inseparably associated with the most reliable and top-quality microscope based imaging solutions.

MetaSystems presented a fully equipped Metafer system with SlideFeeder x80 on two scientific congresses in Latin America (October 2016).