XA TriScore (X/Y/21)

Aneusomy Probe

Order Number
D-5603-100-TC
Package Size
100 µl (10 Tests)
Labels
   
Chromosomes
XY21
Regulatory Status
IVDR

IVDR Certification

This probe is IVDR-certified in compliance with the Regulation (EU) 2017/746 on in vitro diagnostic medical devices (IVDR). For organizational reasons, we currently provide only the IVDD product.

Please use the switch to change to the IVDD product.

IVDDIVDRDiscover all IVDR-certified products

Intended Purpose

The XA TriScore (X/Y/21) enumeration probe is a qualitative, non-automated test for the detection of copy number variations of chromosome X, chromosome Y and chromosome 21 by fluorescence in situ hybridization (FISH). The product is intended for prenatal testing of pregnancies at risk for copy number variations of chromosomes X and chromosome Y and trisomy 21 on methanol/acetic-acid fixed uncultured amniocytes.

Product Description

The XA TriScore (X/Y/21) enumeration probe consists of an aqua-labeled probe hybridizing to the centromere of the X-chromosome, a green-labeled probe hybridizing to the centromere of the Y-chromosome and an orange-labeled probe hybridizing to the DSCR4 gene region at 21q22.1-22.2.

Need assistance or a quote?

Images

XA TriScore (X/Y/21)

XA TriScore (X/Y/21) hybridized to lymphocytes. Two aberrant interphases (47,XY,+21) are shown.

Need assistance or a quote?

Expected Patterns

Expected Pattern 1

Normal Cell (male):
One green (1G), two orange (2O), and one blue (1B) signal.

Expected Pattern 2

Normal Cell (female):
No green (0G), two orange (2O), and two blue (2B) signals.

Expected Pattern 3

Aberrant Cell (male):
One green (1G), three orange (3O), and one blue (1B) signal.

Expected Pattern 4

Aberrant Cell (female):
No green (0G), three orange (3O), and two blue (2B) signals.

Expected Pattern 5

Aberrant Cell (male):
One green (1G), two orange (2O), and two blue (2B) signals.

Expected Pattern 6

Aberrant Cell (male):
Two green (2G), two orange (2O), and two blue (2B) signals.

Expected Pattern 7

Aberrant Cell (female):
No green (0G), two orange (2O), and one blue (1B) signals.

Expected Pattern 8

Aberrant Cell (female):
No green (0G), two orange (2O), and three blue (3B) signals.

Need assistance or a quote?

Downloads

News

MetaSystems DM2019 Largest in History

About 100 guests from 36 countries met on the XVIII. MetaSystems Distributor Meeting (DM) in November to exchange experiences and to get to know new trends and developments at MetaSystems.

MetaSystems DM2019 Largest in History

New MetaSystems Office in Latin America

MetaSystems proudly announces the opening of our first subsidiary in the Southern hemisphere. The new office is located in Buenos Aires, Argentina and bears the name MetaSystems Latinoamérica SAS (MetaSystems LatAm). The foundation has been the response to the growing demand on technical knowledge and 'know how' experienced in the last years all over the Latin American territories. MetaSystems LatAm takes care for the organization of sales, support, and customer relation activities in all countries in Latin America. It will manage distributor companies and contacts in the region, and it will facilitate communication between end-users, distributors and headquarters in Germany.

New MetaSystems Office in Latin America

MetaSystems Workshop in Dehradun, India

A “Hands-on Workshop on FISH and its application in Pathology and Clinical Medicine” was organized by MetaSystems and Department of Pathology, Himalayan Institute of Medical Sciences (HIMS) to demonstrate the applications of FISH in hematological malignancies and solid tumors.

MetaSystems Workshop in Dehradun, India