About 100 guests from 36 countries met on the XVIII. MetaSystems Distributor Meeting (DM) in November to exchange experiences and to get to know new trends and developments at MetaSystems.
MetaSystems DM2019 Largest in History
XL TCL1 BA
Break Apart Probe
- Order Number
- D-5142-100-OG
- Package Size
- 100 µl (10 Tests)
- Chromosome
- 1414
- Regulatory Status
- IVDR
IVDR Certification
This probe is IVDR-certified in compliance with the Regulation (EU) 2017/746 on in vitro diagnostic medical devices (IVDR). For organizational reasons, we currently provide only the IVDD product.
The XL TCL1 BA break-apart probe is a qualitative, non-automated test for the detection of TCL1A/TCL1B-rearrangements at 14q32.1-32.2 by fluorescence in situ hybridization (FISH). The product is intended as a diagnostic aid and assists in disease monitoring. The test population consists of patients with confirmed or suspected T-cell prolymphocytic leukemia (T-PLL). Hybridization is to be performed on methanol/acetic-acid fixed cells derived from bone marrow or peripheral blood.
The XL TCL1 BA break-apart probe consists of an orange-labeled probe hybridizing proximal to the TCL1A/TCL1B gene region at 14q32.1 and a green-labeled probe hybridizing distal to the TCL1A/TCL1B gene region at 14q32.1-14q32.2.
XL TCL1 BA hybridized to lymphocytes. One aberrant interphase nucleus with one fusion signal, and one separate orange and green signal is shown, representing a rearrangement with involvement of the TCL1 gene cluster.
Normal Cell:
Two green-orange colocalization/fusion signals (2GO).
Aberrant Cell (typical results):
One green-orange colocalization/fusion signal (1GO), one separate green (1G) and orange (1O) signal each resulting from a chromosome break in the respective locus.
Second MetaSystems User Day in Altlussheim, Germany
Neon, the outstanding MetaSystems case and image management system, offers many tools and helpful gadgets to streamline routine workflows, for example in cytogenetics labs. The second MetaSystems User Day, addressed to MetaSystems clients from Germany, Austria, and Switzerland, provided in different workshops knowledge helping to unleash the full power of the system.
OOO MetaSystems Russia on the International Scientific Congress 'Genetics of XXI Century'
The Congress 'Genetics of XXI Century' in Moscow, Russia (May 2019) has been one of the most important events for the professional international community of geneticists. Our partner company in Russia OOO MetaSystems considered it a good occasion to present the new camera CoolCube 4 connected to a state-of-the-art Neon system to the public.
